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dc.contributor.authorTarhan, Nevzat
dc.contributor.authorBrown, Elliot
dc.contributor.authorHizli Sayar, Gokben
dc.contributor.authorTan, Oguz
dc.contributor.authorTas, Cumhur
dc.contributor.authorCebi, Merve
dc.date.accessioned2014-11-01T07:30:02Z
dc.date.available2014-11-01T07:30:02Z
dc.date.issued2014
dc.identifier.citationTaş, C., Çebi, M., Tan, O., Hızlı Sayar, G., Tarhan, N.,& Brown, E. (2014). EEG power,cordance and coherence differences between unipolar and bipolar depression. Journal of Affective Disorders; 172(2015): 184-190.tr_TR
dc.identifier.urihttp://earsiv.uskudar.edu.tr/xmlui/handle/123456789/358
dc.identifier.urihttp://www.jad-journal.com/article/S0165-0327(14)00623-5/abstract
dc.description.abstractIntroduction Understanding the biological underpinnings of unipolar (UD) and bipolar depression (BD) is vital for avoiding inappropriate treatment through the misdiagnosis of bipolar patients in their first depressive episode. One plausible way to distinguish between UD and BD is to compare EEG brain dynamics to identify potential neurophysiological biomarkers. Here we aimed to test group differences in EEG power, cordance and coherence values between UD and BD. Methods Twenty-five bipolar and 56 unipolar depression patients were recruited. Sociodemographic and clinical variables were collected in addition to resting state EEG. Data was analyzed with multivariate and repeated analyses of variance where parametric assumptions were met. Results Accordingly, we did not find any differences in the EEG absolute power and frontal asymmetry indexes between UD and BD. Regarding cordance, significant group differences were observed in the right theta cordance values (p=0.031). Regarding coherence, BD patients (as compared to UD) exhibited greater central–temporal theta (p=0.003), and parietal–temporal alpha (p=0.007) and theta (p=0.001) coherence. Lastly, less alpha coherence in BD was present at right frontal–central (p=0.007) and central inter-hemispheric (p=0.019) regions. Conclusions Our results demonstrate that EEG cordance and coherence values have potential to discriminate between UD and BD. The loss of temporal synchronization in the frontal interhemispheric and right sided frontolimbic neuronal networks may be a unique feature that distinguishes between BD and UD.tr_TR
dc.language.isoengtr_TR
dc.relation.ispartofseriesSCI-E;
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.jad.2014.10.001tr_TR
dc.subjectDepressiontr_TR
dc.subjectElectroencephalographytr_TR
dc.subjectPowertr_TR
dc.subjectHemispheric asymmetrytr_TR
dc.subjectCordancetr_TR
dc.subjectCoherencetr_TR
dc.titleEEG power,cordance and coherence differences between unipolar and bipolar depressiontr_TR
dc.typeArticletr_TR
dc.relation.journalJournal of Affective Disorderstr_TR
dc.contributor.departmentÜsküdar Üniversitesi, İnsan ve Toplum Bilimleri Fakültesi, Psikoloji Bölümütr_TR
dc.contributor.authorIDTR188323tr_TR


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