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dc.contributor.authorBrown, Elliot
dc.contributor.authorKuzu, Duygu
dc.contributor.authorRoelofs, Karin
dc.contributor.authorBrüne, Martin
dc.contributor.authorTas, Cumhur
dc.contributor.authorEsen Danaci, Aysen
dc.date.accessioned2015-01-02T15:37:55Z
dc.date.available2015-01-02T15:37:55Z
dc.date.issued2014
dc.identifier.citationBrown E., Tas C., Kuzu D., Esen-Danaci A, Roelofs K., Brüne M., (2014). Social approach and avoidance behaviour is modulated by endogenous oxytocin in schizophrenia. Psychiatry Research, 219(3), 436-442tr_TR
dc.identifier.urihttp://earsiv.uskudar.edu.tr/xmlui/handle/123456789/445
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/25048758
dc.description.abstractPatients with schizophrenia suffer from dysfunctional social behaviour. Social approach and avoidance (AA) has been associated with motor responses,as the affective valence and gaze direction of facial stimuli can bias push and pull motor tendencies. The aim of this study was to investigate the role of endogenous oxytocin in social AA behaviour in schizophrenia. Basal plasma oxytocin levels were collected from 28 patients who were then given a joystick-based Approach Avoidance Task(AAT). Reaction times were recorded and AAT effect scores calculated for responses to happy and angry faces, which either had direct or averted gaze. Individual differences in basal oxytocin had a significant relationship with AAT responses, and patients with higher levels of oxytocin tended to avoid angry faces more. Furthermore, greater avoidance of angry faces was correlated with more severepsychotic (positive and general) symptoms and greater paranoia. This suggests that the endogenous effects of oxytocin may be specific to the interpretation of negative threatening emotions in schizophrenia patients and also provides evidence that psychotic symptoms and paranoia can impact on social AA behaviour by heightening threat avoidance.tr_TR
dc.language.isoengtr_TR
dc.relation.ispartofseriesuluslararası diğer;
dc.relation.isversionof10.1016/j.psychres.2014.06.038tr_TR
dc.subjectOxytocintr_TR
dc.subjectSchizophreniatr_TR
dc.subjectParanoiatr_TR
dc.subjectSocial behaviourtr_TR
dc.subjectThreat avoidancetr_TR
dc.titleSocial approach and avoidance behaviour for negative emotions is modulated by endogenous oxytocin and paranoia in schizophreniatr_TR
dc.typeArticletr_TR
dc.relation.journalPsychiatry Researchtr_TR
dc.contributor.departmentÜsküdar Üniversitesi, İnsan ve Toplum Bilimleri Fakültesi, Psikoloji Bölümütr_TR
dc.contributor.authorIDTR188323tr_TR


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