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dc.contributor.authorTarhan, Nevzat
dc.contributor.authorHizli Sayar, Gokben
dc.contributor.authorTan, Oguz
dc.contributor.authorOzten, Eylem
dc.date.accessioned2014-09-29T10:25:23Z
dc.date.available2014-09-29T10:25:23Z
dc.date.issued2013
dc.identifier.citationTranscranial magnetic stimulation for treating depression in elderly patients. G. Hızlı Sayar, E. Ozten, O. Tan, N. Tarhan Neuropsychiatric Disease and Treatment 2013, 9:501–504. http://dx.doi.org/10.2147/NDT.S44241tr_TR
dc.identifier.urihttp://earsiv.uskudar.edu.tr/xmlui/handle/123456789/243
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/23723700
dc.description.abstractPurpose: The aim of the study reported here was to examine the safety and effectiveness of high-frequency repetitive transcranial magnetic stimulation (rTMS) in elderly patients with depression. Patients and methods: Sixty-five depressed elderly patients received rTMS over their left prefrontal cortex for 6 days per week, from Monday to Saturday, for 3 weeks. The rTMS intensity was set at 100% of the motor threshold and 25 Hz stimulation with a duration of 2 seconds and was delivered 20 times at 30-second intervals. A full course comprised an average of 1000 magnetic pulses. Depression was rated using the Hamilton Depression Rating Scale (HAMD) before and after treatment. Response was defined as a 50% reduction in HAMD score. Patients with HAMD scores , 8 were considered to be in remission. Results: The mean HAMD score for the study group decreased from 21.94 ± 5.12 before treatment to 11.28 ± 4.56 after rTMS (P , 0.001). Following the treatment period, 58.46% of the study group demonstrated significant mood improvement, as indexed by a reduction of more than 50% on the HAMD score. Nineteen of these 38 patients attained remission (HAMD score , 8), while 41.54% of all study patients achieved a partial response. None of the patients had a worsened HAMD score at the end of the treatment. Treatment was generally well tolerated and no serious adverse effects were reported. Conclusion: In this study, rTMS was found to be a safe, well-tolerated treatment, and a useful adjunctive treatment to medications in elderly treatment-resistant depressed patients. This study contributes to the existing evidence on the antidepressant effect of rTMS in the treatment of depression in patients over 60 years of agetr_TR
dc.language.isoengtr_TR
dc.relation.ispartofseriesSCI-expanded;
dc.relation.isversionof10.2147/NDT.S44241tr_TR
dc.subjecthigh-frequency repetitive TMStr_TR
dc.subjectrTMStr_TR
dc.subjectHamilton Depression Rating Scaletr_TR
dc.titleTranscranial magnetic stimulation for treating depression in elderly patientstr_TR
dc.typeArticletr_TR
dc.relation.journalNeuropsychiatric Disease and Treatmenttr_TR
dc.contributor.departmentÜsküdar Üniversitesi, NPSUAMtr_TR
dc.contributor.authorIDTR25221tr_TR


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