EFFECT OF ANAEROBIC AND AEROBIC EXERCISE TOWARD SEROTONIN IN RAT BRAIN TISSUE
Juliansyah, Rahmad Aswin
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Physical exercise plays a substantial role in maintaining our heath. In the molecular level, physical exercise induces the release of neurotransmitter, such as serotonin. Lack of serotonin could lead to stress or depression condition. We assumed that physical exercise could increase serotonin level in the brain. Therefore, this study aimed to investigate the effect of anaerobic and aerobic exercise toward serotonin level in male Wistar rat brain tissue. Twenty-eight male Wistar rats were divided into seven groups consist of control; 1x, 3x, 7x of aerobic exercise; and 1x, 3x, 7x of anaerobic exercise which conducted in a week. A rat treadmill was used at speed 35 m/min during 20 min for anaerobic exercise, and it was used at speed 20 m/min during 30 min for aerobic exercise. Serotonin level was measured using ST/5-HT (Serotonin/5-Hydroxytryptamine) ELISA Kit. Significant differences between treatments were tested by ANOVA (α = 5%). In contrast, both of anaerobic and aerobic exercise had lower serotonin level than the control.