Show simple item record

dc.contributor.authorDilbaz, Nesrin
dc.contributor.authorTarhan, Nevzat
dc.contributor.authorHizli Sayar, Gokben
dc.contributor.authorOzten, Eylem
dc.contributor.authorKagan, Gaye
dc.date.accessioned2014-09-25T17:10:43Z
dc.date.available2014-09-25T17:10:43Z
dc.date.issued2013
dc.identifier.citationTranscranial magnetic stimulation during pregnancy. G. Hızlı Sayar, E. Özten, G. Kağan, N. Dilbaz, N. Tarhan. Archives of Women’s Mental Health 2013. DOI: 10.1007/s00737-013-0397-0tr_TR
dc.identifier.urihttp://earsiv.uskudar.edu.tr/xmlui/handle/123456789/237
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/24248413
dc.description.abstractThe aim of the present study was to assess the safety and effectiveness of high-frequency repetitive transcranial magnetic stimulation (rTMS) in pregnant patients with depression. Thirty depressed pregnant patients received rTMS over the left prefrontal cortex for 6 days in a week, from Monday to Saturday for 3 weeks. The rTMS intensity was set at 100 % of the motor threshold. A 25-Hz stimulation with a duration of 2 s was delivered 20 times with 30-s intervals. A session comprised 1,000 magnetic pulses. Depression was rated using the 17-item Hamilton depression rating scale (HAMD) before and after treatment. Response was defined as a 50%reduction of theHAMDscore. Patients with HAMD scores less than 8 were considered to be in remission. Themean HAMD score for the study group decreased from 26.77±5.58 to 13.03±6.93 (p <0.001) after 18 sessions of rTMS. After the treatment period, 41.4 % of the study group demonstrated significant mood improvements as indexed by a reduction of more than 50 % on the HAMD score. In addition, 20.7 % attained remission (HAMD score<8), 34.5 % achieved a partial response, and 3.4 % had worsening in HAMD scores at the end of treatment. Treatment was well tolerated, and no significant adverse effects were reported. rTMS was well tolerated and found to be statistically and clinically effective in pregnant patients with treatmentresistant depression. This study contributed to the existing evidence of the antidepressant effect of rTMS in the treatment of depression in pregnancy.tr_TR
dc.language.isoengtr_TR
dc.relation.ispartofseriesSCI-expanded;
dc.relation.isversionof10.1007/s00737-013-0397-0tr_TR
dc.subjectRepetitive transcranial magnetic stimulationtr_TR
dc.subjectrTMStr_TR
dc.subjectPregnancytr_TR
dc.subjectDepressiontr_TR
dc.subjectTreatmenttr_TR
dc.titleTranscranial magnetic stimulation during pregnancy.tr_TR
dc.typeArticletr_TR
dc.relation.journalArchives of Women’s Mental Healthtr_TR
dc.contributor.departmentÜsküdar Üniversitesi, NPSUAMtr_TR
dc.contributor.authorIDTR25221tr_TR


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record