Moleküler Biyoloji ve Genetik Bölümü: Recent submissions
Toplam kayıt 36, listelenen: 1-20
-
Synthesis of Novel Schiff Base Cobalt (II) and Iron (III) Complexes as Cathode Catalysts for Microbial Fuel Cell Applications
(2019-05-07)In this study, the synthesis and characterization of a new Schiff base and its cobalt(II) and iron(III) complexes were performed fully characterized by common spectroscopic techniques such as 1H-NMR, 13C-NMR, FT-IR, UV–Vis ... -
Türk Milli Bisikletçilerde Alfa- Aktinin-3 R577X Polimorfizm Dağılımının Belirlenmesi
(2017)Atletik performans ile ilgili en önemli ve belki de en fazla incelenen genetik belirteç, alfa- aktinin-3 proteinin (Actn3) kodlayan ACTN3 genidir. Çalışmamızda 13’ü bayan, 23’ü erkek toplam 36 milli bisikletçide ACTN3 R577X ... -
Hydrogen production profiles using furans in microbial electrolysis cells
(2017)Microbial electrochemical cells including microbial fuel cells (MFCs) and microbial electrolysis cells (MECs) are novel biotechnological tools that can convert organic substances in wastewater or biomass into electricity ... -
Lesions of the paraventricular thalamic nucleus attenuates prepulse inhibition of the acoustic startle reflex
(2016)The paraventricular thalamic nucleus (PVT) is a midline nucleus with strong connections to cortical and subcortical brain regions such as the prefrontal cortex, amygdala, nucleus accumbens (NAc) and hippocampus and ... -
Is It Possible To Understand The Brain By Only Neuroscience? New Expansions And Approaches From Neurological Sciences To Social Sciences In The Brain Century
(2016)Geçtiğimiz yüzyıl boyunca beyni anlamaya yönelik çalışmalar tıp alanında ve özellikle nöroanatomi, nöroloji ve beyin cerrahisi alanlarında yoğunlaşmıştı. Yüzyılın ikinci yarısından itibaren çok önemli bilimsel keşiflerle ... -
Investigation of the role of alpha-2 adrenergic receptors on prepulse inhibition of acoustic startle reflex in rats
(2016)Objectives: Alpha-2 adrenergic receptors target several behavioral functions. These receptors may connect with the brain pathways mediating sensorimotor gating system that associate with psychoses, and the literature ... -
Dexmedetomidine induces conditioned place preference in rats: Involvement of opioid receptors
(2016)Dexmedetomidine (DEX) is an alpha-2 adrenergic agonist drug recently introduced to anesthesia practice. Certain agents used in anesthesia practice have been associated with abuse and addiction problems; however, few ... -
Modeling Symptoms of Attention-Deficit Hyperactivity Disorder in a Rat Model of Fetal Alcohol Syndrome
(2016)Aims: Several studies indicate the similarity between the symptoms of fetal alcohol syndrome and attention-deficit hyperactivity disorder (ADHD). This study hypothesized that prenatal exposure to ethanol (EtOH) can be ... -
Nörokimyasal iletim
(2012) -
Varenicline disrupts prepulse inhibition only in high-inhibitory rats.
(2014)Varenicline, a widely used smoking cessation drug, has partial agonistic activity at α4β2 nicotinic receptors, and full agonistic activity at α7 nicotinic receptors. Thus it may interact with cognitive processes and may ... -
Social interaction of rats is related with baseline prepulse inhibition level.
(2014)The symptoms of schizophrenia are evaluated in three general categories: positive, negative and cognitivesymptoms. Disruption of prepulse inhibition (PPI) of the acoustic startle reflex is commonly used to modelpositive ... -
The pharmacological importance of agmatine in the brain
(2012)Agmatine is a polyamine that is produced via decarboxylation of l-arginine by the enzyme arginine decarboxylase. It binds to various receptors and has been accepted as a novel neurotransmitter in brain. In experimental ... -
Alzheimer disease and neuroplasticity: New approaches and new targets in pharmacotherapy.
(2012)Alzheimer disease (AD) is the major cause of dementia in the aged individuals. It is a neurodegenerative disorder characterized by apoptosis and loss of neurons resulting in synaptic dysfunction in central pathways ... -
The antinociceptive effects of intravenous tianeptine in colorectal distension-induced visceral pain in rats: The role of 5-HT3 Receptors.
(2012)Tianeptine is an unusual tricyclic antidepressant drug. In this study, we aimed to investigate the antinociceptive effect of tianeptine on visceral pain in rats and to determine whether possible antinociceptive effect ... -
Induced locomotor hyperactivity on ethanol withdrawal syndrome in rats is inhibited by quetiapine.
(2012)Our aim is to investigate the effects of two atypical antipsychotics; quetiapine and olanzapine on locomotor activity that is a sign of ethanol withdrawal syndrome in rats. Adult male Wistar rats were subjects. Ethanol ... -
Chronic melatonin treatment reverses disruption of prepulse inhibition in pinealectomized and pinealectomized-plus-ovariectomized rats.
(2013)Although melatonin has been implicated in several neurophysiological systems, data on the relationship of melatonin with psychosis such as schizophrenia are limited and contradictory. Chronic effects of melatonin on ... -
Psikotrop ilaç etkileşmeleri
(2012) -
Agomelatine strongly interacts with zwitterionic DPPC and charged DPPG membranes.
(2014)Depression is one of the most common psychiatric diseases in the population. Agomelatine is a novel antidepressant drug with melatonin receptor agonistic and serotonin 5-HT2C antagonistic properties. Furthermore, being ... -
A new target for diagnosis and treatment of CNS disorders: Agmatinergic system.
(2012)A polyamine agmatine is produced through decarboxylation of L -arginine by the enzyme arginine decarboxylase and is a new neurotransmitter in central nervous system (CNS). It has been suggested that agmatine has analgesic, ...